The Sinus and Allergy Center is honored to have received notice that it has been awarded a major NIH-supported program project grant to fund a collaborative effort between Northwestern University, The University of Chicago, the Geisinger Health System and the Johns Hopkins Bloomberg School of Public Health to study the epidemiology, genetics and pathobiology of chronic rhinosinusitis. The collaborative group, collectively known as the Chronic Rhinosinusitis Integrative Studies Program (CRISP) is the only program project grant (P01) recipient in the United States studying this common but poorly understood disease. Program project grants are more complex in scope and budget than individual research grants. While individual research grants are awarded to support the work of one principal investigator who, with supporting staff, is addressing a scientific problem, program project grants are available to a group of several investigators with differing areas of expertise who wish to collaborate in research by pooling their talents and resources. These resources will fund continued studies examining the genetic, environmental, molecular and immunologic underpinnings of chronic rhinosinusitis in order to discover new means of treating this disease.